Past Research Projects

Past Research Projects

Examples of Past Research Projects:

The Transmission and Fitness of Drug Resistant HIV

Agency: NIH/NIAID

Agency Award Number: R01AI047033

To determine the prevalence of transmitted drug resistant variants including those that may be resistant to new antiretroviral targets such as inhibitors of viral fusion (enfuvirtide) and integration.

A Multi-Site Investigation into the Effect of HIV Clade on Neurocognitive Impairment

Agency: NIH/NIMH

Agency Award Number: R01MH083552

To characterize and compare the burden of HIV associated neurocognitive disorders (HAND) occurring among individuals living in Brazil, China, India, Romania and the United States, and to evaluate the neurovirulent and neurotropic genotypic determinants between subtypes.

Mannose Binding Lectin in Neuroinflammation and NeuroAIDS

Agency: NIH/NIMH

Agency Award Number: R01MH085608

To determine the novel role of mannose binding lectin in susceptibility of HIV-1 infection in brain and related neuroinflammation, viral protein accumulation and neurocognitive impairment.

Navy NP Study

Agency: Navy

Agency Award Number:

Mechanisms of Neuroprotection in HIV Encephalitis

Agency: NIH/NIMH

Agency Award Number: R01MH062962

To investigate the role of alterations in CDK5 signaling pathway in the molecular mechanisms of synapto-dendritic damage triggered by HIV proteins, and to determine the involvement of the CDK5 signaling pathway in the mechanisms of defective neurogenesis triggered by HIV proteins.

NeuroAIDS in Cameroon: Molecular Determinants

Agency: NIH/NIMH

Agency Award Number: R21MH080611

To investigate whether infections with HIV isolates that have a particular genetic characteristic makes patients more susceptible to neurocognitive disorders.

Creating a Pediatric Imaging-Genomics Data Resource

Agency: NIH/NIDA

Agency Award Number: RC2DA029475

To address the discrepancy between currently available imaging-genetics data in children of different ages and those available in adults.

 

  1. Methamphetamine Abuse, Acute HIV Infection, GALT Destruction, and HIV Associated Neurocognitive Disorder (HAND)
  2. ARC: Biomarkers/NC Impairment
  3. COMT Genotype and Risky Decision Making in HIV and Methamphetamine Dependence
  4. Multimodel Correlation of Imaging Markers and Neuropathogenesis of NeuroAIDS
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