Past Research Projects
Past Research Projects
Examples of Past Research Projects:
Agency: NIH/NIAID
Agency Award Number: R01AI047033
To determine the prevalence of transmitted drug resistant variants including those that may be resistant to new antiretroviral targets such as inhibitors of viral fusion (enfuvirtide) and integration.
Agency: NIH/NIMH
Agency Award Number: R01MH083552
To characterize and compare the burden of HIV associated neurocognitive disorders (HAND) occurring among individuals living in Brazil, China, India, Romania and the United States, and to evaluate the neurovirulent and neurotropic genotypic determinants between subtypes.
Agency: NIH/NIMH
Agency Award Number: R01MH085608
To determine the novel role of mannose binding lectin in susceptibility of HIV-1 infection in brain and related neuroinflammation, viral protein accumulation and neurocognitive impairment.
Agency: Navy
Agency Award Number:
Agency: NIH/NIMH
Agency Award Number: R01MH062962
To investigate the role of alterations in CDK5 signaling pathway in the molecular mechanisms of synapto-dendritic damage triggered by HIV proteins, and to determine the involvement of the CDK5 signaling pathway in the mechanisms of defective neurogenesis triggered by HIV proteins.
Agency: NIH/NIMH
Agency Award Number: R21MH080611
To investigate whether infections with HIV isolates that have a particular genetic characteristic makes patients more susceptible to neurocognitive disorders.
Agency: NIH/NIDA
Agency Award Number: RC2DA029475
To address the discrepancy between currently available imaging-genetics data in children of different ages and those available in adults.





Dr. Scott Letendre, MD, presented at the HIV and Aging Symposium 2026.