Raeanne C. Moore and colleagues published a paper on "Objective and subjective sleep measures are associated with neurocognition in aging adults with and without HIV".

Studies have shown that poor sleep is related to worse cognitive functioning (e.g., memory, attention) in older adults and persons with HIV. However, the relationship between sleep and cognitive functioning has not been well studied in older people with HIV. In this study we examined how sleep relates to cognitive functioning in people aged 50 and older with and without HIV. We gave 84 participants paper and pencil cognitive tests to measure cognitive functioning. To measure sleep, we gave participants watches (similar to a Fitbit watch) to measure their sleep at home for 14 days. We also had participants rate their own sleep quality using a questionnaire.

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Raeanne C. Moore and colleagues published a paper on "Daily Activities Related to Mobile Cognitive Performance in Middle-Aged and Older Adults: An Ecological Momentary Cognitive Assessment Study".

Working, reading and other cognitively stimulating activities are related to better cognitive functioning. Conversely, studies have found that passive activities such as watching television are related to worse cognitive functioning. One problem with the current research on understanding the relationships between daily activities and cognitive functioning is that cognitive testing is usually done on a single day in a lab, which may not reflect real world cognitive performance. In this study, we used smartphones to test participants’ cognitive functions multiple times a day immediately after different types of activity (i.e., at different times during the day, participants’ smartphones would survey what they were doing and then ask them to complete a short cognition test.). The cognitive abilities we tested were executive functioning and learning.

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Several HNRP investigators contributed to the International Neuropsychological Society (INS) Annual Meeting in San Diego (virtual event) on February 2-5, 2021. This year's theme was: From Autism to Alzheimer's: New Perspectives in Neuropsychology. HNRP researchers presented on topics such as cognition, HIV, substance use, medical measures and behavior.

Posters/Presentations:

Breton J, Kamalyan L, Paredes AM, Guarena LA, Watson WM, Cherner M, Moore RC, Marquine MJ. Psychological acculturation and cognition among older Latinos living with and without HIV. (poster)

Campbell LM, Parrish E, Heaton A, Swendsen J, Depp CA, Moore RC. The Relationship Between Contextual Factors, Performance, and Validity of Smartphone-Based Mobile Cognitive Tests of Executive Function and Learning. (poster)

Fisher A, Campbell LM, Sun-Suslow N, Kohli M, Tang B, Lee EE, Heaton A, Moore RC. Intra-individual variability in objectively-measured sleep quality is associated with worse cognition in middle-aged and older adults with and without HIV. (poster)

Guarena LA, Kamalyan L, Morgan EE, Watson WM, Umlauf A, Heaton RK, Marquine MJ. Impact of emotional health on cognition amongst Hispanic and Non-Hispanic white people living with HIV. (poster)

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CROI 2021 was held from March 6 to March 10, 2021. The meeting took place virtually. The HNRP had a strong showing with research on various aspects of HIV infection.

Listing of posters and presentations:

Ellis R, Paolillo EW, Saloner R, Letendre S, Moore DJ, Heaton RK. Higher Comorbidity Burden Predicts Worsening Neurocognition in People with HIV.

Letendre S, Ellis RJ, Tang B, Franklin D, Sacktor N, Rubin L, Morgello S, McCutchan JA, Marra C, Gelman BB, Collier A, Clifford D, Heaton RK. 12-Year Cognitive Decline is Associated with Lung Disease, Diabetes, and Depression.

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