Current Research Projects - Blog Style

Agency: NIH/NIMH

Agency Award Number: 5R01MH062962-08

To investigate the role of alterations in CDK5 signaling pathway in the molecular mechanisms of synapto-dendritic damage triggered by HIV proteins, and to determine the involvement of the CDK5 signaling pathway in the mechanisms of defective neurogenesis triggered by HIV proteins.

Agency: NIH/NIMH

Agency Award Number: 5R21MH080611-02

To investigate whether infections with HIV isolates that have a particular genetic characteristic makes patients more susceptible to neurocognitive disorders.

Agency: NIH/NIDA

Agency Award Number: 1RC2DA029475-01

To address the discrepancy between currently available imaging-genetics data in children of different ages and those available in adults.

 

Agency: NIH/NIDA

Agency Award Number: Suppl

To examine whether active METH use during the acute phase of HIV infection worsens the depletion of gut-associated lymphocyte tissue (GALT) and therefore increases the risk of micorbial translocation, inflammatory response, and neurocognitive impairment.

Agency: NIH/NIMH

Agency Award Number: Suppl

An administrative supplement to evaluate the relationship between biomarkers assessed in various fluids/compartments and the development of, or recovery from, HIV-associated neurocognitive disorders.

Agency: NIH/NIDA

Agency Award Number: 1R01DA026334-01A1

To investigate the effects of COMT genotype on executive functioning, preexisting impulsive traits, measurable behaviors indicating impulsivity and novelty seeking, as well as decision-making choices, on HIV risk behaviors among individuals with METH dependence and/or HIV infection.

 

Agency: NIH/NIMH

Agency Award Number: 5R01MH84756-012

To conduct a multi-parametric examination of neuropathogenetic phenomena that are induced by HIV infection, correlating markers of the disease revealed by different imaging modalities (in vivo and ex vivo) with those localized by specific histological methods to improve our understanding of HIV neuropathogenesis towards the earliest detection by non-invasive means of neurological signs and response to treatment.

 

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