CHARTER Manuscript Highlighted in Neurology

Dr. Igor Grant and the CHARTER Group have a featured article in the June 2014 issue of Neurology,  “Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline”.  Their study presents further evidence that HIV-associated neurocognitive disorders remain prevalent despite combination antiretroviral therapy.  The study demonstrates that early asymptomatic neurocognitive impairment (ANI) confers an increased risk and faster development of functional/symptomatic decline in individuals with HIV disease progression.  These findings highlight the importance of identifying those with ANI in the clinic early on to offer an opportunity to modify treatment to delay progression to symptomatic/functional decline.

Click Here for link to Pubmed - and full article when available in Pubmed Central.

To Cite:

Grant I, Franklin DR, Deutsch R, Woods SP, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Heaton RK, for the CHARTER Group.  (2014). Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline. Neurology, 82(23), 2055-2062. PMID: 24814848