Brookie Best Appointed to Office of AIDS Research Advisory Council

HNRP Investigator Brookie M. Best, PharmD, MAS, Associate Professor of Clinical Pharmacy and Pediatrics, Associate Dean for Admissions and Outreach, University of California, San Diego received an appointment to the Office of AIDS Research Advisory Council (OARAC) on July 1, 2013.  She served as a scientific member with pharmacology expertise on the working group “Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission Guidelines".

The Office of AIDS Research Advisory Council provides advice to the Director of the Office of AIDS Research on the planning, coordination, and evaluation of research and other activities in respect to AIDS conducted or supported by the NIH.  Dr. Best's research efforts include maternal-fetal clinical pharmacology with a focus on studying anti-HIV drugs in infants, children, adolescents, non-pregnant adults, and pregnant women.

Examples of HNRP Related Publications:

Best BM, Letendre SL, Koopmans P, Rossi SS, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Simpson DM, Capparelli EV, Ellis RJ, Grant I, and the CHARTER Study Group.  (2012). Low CSF concentrations of the nucleotide HIV reverse transcriptase inhibitor, Tenofovir. Journal of AIDS, 59(4), 376-381. PMID: 22217676  PMCID: PMC3299895

Best B, Koopmans P, Letendre S, Capparelli E, Rossi S, Clifford D, Collier A, Gelman B, Mbeo G, McCutchan J, Simpson D, Haubrich R, Ellis R, Grant I, and the CHARTER Group.  (2011). Efavirenz concentrations in cerebrospinal fluid exceed wild-type HIV IC50. Journal of Antimicrobial Chemotherapy, 66, 354-357. PMID: 21098541  PMCID: PMC3019085 

Best BM, Letendre SL, Brigid E, Clifford DB, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Simpson DM, Ellis R, Capparelli EV, Grant I, and the CHARTER Group.  (2009). Low atazanavir concentrations in cerebrospinal fluid. AIDS, 23(1), 83-87. PMID: 19050389  PMCID: PMC2642983